Educational Articles
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Cyclophosphamide is given by mouth or injection and is used off label to treat various cancers such as lymphoma, leukemia, carcinoma, and sarcoma. Common side effects include hair loss and hair coat changes. Do not use in pets that are allergic to it or that cannot be sufficiently monitored during treatment, are pregnant or lactating, have urinary obstruction, infection, bone marrow dysfunction, or have had an episode of blood in the urine that is not associated with a bladder infection. If a negative reaction occurs, please call your veterinary office.
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Cyclosporine ophthalmic ointment is an immunosuppressant used in the treatment of eye diseases suspected to be immune-related, including keratoconjunctivitis sicca (KCS) and other inflammatory conditions of the eye. Cyclosporine comes as an ophthalmic ointment but may sometimes be compounded into a higher concentration ophthalmic solution for pets not responding to the ointment. It is important to remember that it may take days to weeks to notice improvement. Do not stop giving the medication without asking your veterinarian. If signs of serious side effects or immune suppression occur, contact your veterinarian immediately.
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Cyclosporine is given by mouth and is used to treat atopic dermatitis in dogs and cats. It has also been used off-label to treat other types of immune-mediated conditions. Give as directed. The most common side effects include stomach upset, such as vomiting, diarrhea, and decreased appetite. Do not use in pets with severe infections, a history of cancer, allergies to the medication, that are nursing or pregnant, or in pets younger than six months old. If a negative reaction occurs, contact your veterinarian.
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Cyproheptadine is given by mouth and is used off label to treat allergic skin conditions, certain toxicities, and to stimulate appetite. Give as directed by your veterinarian. Common side effects include sleepiness, increased appetite, and dry mouth. Do not use in pets that are allergic to it or pets undergoing skin allergy testing within the next two weeks. If a negative reaction occurs, please call your veterinary office.
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Cytarabine is a chemotherapy medication commonly used off label to treat blood cancers and brain inflammation. It is an injectable solution usually given in the vein by a veterinary professional. Common side effects include gastrointestinal upset and low blood cell counts. This medication should not be used or used with caution in pets with liver or kidney disease, those that have an allergy to this medication, and pregnant/lactating pets. If a negative reaction occurs, call your veterinary office.
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Decoquinate is given by mouth and is used off label in dogs to prevent coccidia infections. Side effects are uncommon. Do not use in animals that are allergic to it or to treat coccidia infections (only use as a preventive).
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Deracoxib (brand name Deramaxx) is a non-steroidal anti-inflammatory drug (NSAID) used in dogs after surgery to reduce the pain associated with surgery (e.g., orthopedic and dental surgeries), as well as for the treatment of osteoarthritis. This article discusses possible side effects, risk factors, drug interactions, monitoring, and proper storage.
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Deslorelin is injected under the skin or into the muscle and is used on and off-label in horses, ferrets, and dogs to treat reproductive and adrenal conditions (off-label use in the U.S. is prohibited). Give as directed. Common side effects include swelling, sensitivity, redness, and warmth at the injection site. Do not use in pets that are allergic to it. If a negative reaction occurs, please call the veterinary office.
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Desmopressin is administered into the eye or is given as an injection and is used off label to treat diabetes insipidus and von Willebrand disease. Give as directed by your veterinarian. Side effects are uncommon but may include irritation upon application to the eye. Do not use in pets that are allergic to it or pets that are prone to blood clots, such as those with heart disease. If a negative reaction occurs, please call your veterinary office.
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Desoxycorticosterone pivalate (DOCP) (brand name Percorten-V®, Zycortal®) is a steroid hormone replacement therapy used to treat primary hypoadrenocorticism (Addison’s disease) in dogs. Extra-label (off-label) lower dosages of DOCP (i.e., lower dose, longer dosing interval, or both) can be used to control the balance of blood electrolyte levels. DOCP has also been used extra-label to treat hypoadrenocorticism in cats.
